Degree of chemical functionalization of carbon nanotubes determines tissue distribution and excretion profile.

نویسندگان

  • Khuloud T Al-Jamal
  • Antonio Nunes
  • Laura Methven
  • Hanene Ali-Boucetta
  • Shouping Li
  • Francesca M Toma
  • M Antonia Herrero
  • Wafa' T Al-Jamal
  • Huub M M ten Eikelder
  • Julie Foster
  • Stephen Mather
  • Maurizio Prato
  • Alberto Bianco
  • Kostas Kostarelos
چکیده

Getting rid of the tubes: An assessment of the retention of functionalized multi-walled carbon nanotubes (MWNTs) in the organs of mice was carried out using single photon emission computed tomography and quantitative scintigraphy (see scheme). Increasing the degree of functionalization on MWNTs enhanced renal clearance, while lower functionalization promoted reticuloendethelial system accumulation.

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عنوان ژورنال:
  • Angewandte Chemie

دوره 51 26  شماره 

صفحات  -

تاریخ انتشار 2012